Development of a structure determination method using a multidrug-resistance regulator protein as a framework.

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第一作者： Takashi,Matsumoto

第一单位： Rigaku Corporation, 3-9-12 Matsubara-cho, Akishima, Tokyo, 196-8666, Japan. Electronic address: t-matumo@rigaku.co.jp.

作者： Takashi,Matsumoto ^[1] ; Ryosuke,Nakashima ^[2] ; Akihito,Yamano ^[3] ; Kunihiko,Nishino ^[2]

作者单位： Rigaku Corporation, 3-9-12 Matsubara-cho, Akishima, Tokyo, 196-8666, Japan. Electronic address: t-matumo@rigaku.co.jp. ^[1] Institute of Scientific and Industrial Research, Osaka University, 8-1 Mihogaoka, Ibaraki, Osaka, 567-0047, Japan. ^[2] Rigaku Corporation, 3-9-12 Matsubara-cho, Akishima, Tokyo, 196-8666, Japan. ^[3]

关键词 Crystalline sponge method Framework In-house X-ray system Multisite binding pocket RamR X-ray crystal structure

主题词结晶学, X线(Crystallography, X-Ray);亲水和疏水相互作用(Hydrophobic and Hydrophilic Interactions);配体(Ligands);模型, 分子(Models, Molecular);分子结构(Molecular Structure);多药耐药相关蛋白质类(Multidrug Resistance-Associated Proteins)

DOI 10.1016/j.bbrc.2019.08.070

PMID 31431261

发布时间 2020-06-22

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