SF3B2-Mediated RNA Splicing Drives Human Prostate Cancer Progression.-论文-万方医学网

作者： Norihiko,Kawamura ^[1] ; Keisuke,Nimura ^[2] ; Kotaro,Saga ^[3] ; Airi,Ishibashi ^[1] ; Koji,Kitamura ^[1] ; Hiromichi,Nagano ^[1] ; Yusuke,Yoshikawa ^[4] ; Kyoso,Ishida ^[1] ; Norio,Nonomura ^[5] ; Mitsuhiro,Arisawa ^[1] ; Jun,Luo ^[6] ; Yasufumi,Kaneda ^[2]

作者单位： Division of Gene Therapy Science, Osaka University Graduate School of Medicine, Suita, Osaka, Japan. ^[1] Department of Urology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan. ^[2] Division of Gene Therapy Science, Osaka University Graduate School of Medicine, Suita, Osaka, Japan. nimura@gts.med.osaka-u.ac.jp kanedy@gts.med.osaka-u.ac.jp. ^[3] Department of Otorhinolaryngology-Head and Neck Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan. ^[4] Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka, Japan. ^[5] Department of Gynecology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan. ^[6] James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, Maryland. ^[7]

主题词腺癌(Adenocarcinoma);氨基酸特征结构(Amino Acid Motifs);动物(Animals);计算机模拟(Computer Simulation);疾病恶化(Disease Progression);环氧化合物(Epoxy Compounds);外显子(Exons);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);大环内酯类(Macrolides);男(雄)性(Male);小鼠(Mice);小鼠, 近交NOD(Mice, Inbred NOD);小鼠, SCID(Mice, SCID);肿瘤侵润(Neoplasm Invasiveness);肿瘤蛋白质类(Neoplasm Proteins);睾丸切除术(Orchiectomy);表型(Phenotype);前列腺肿瘤(Prostatic Neoplasms);蛋白质亚型(Protein Isoforms);RNA剪接(RNA Splicing);RNA, 信使(RNA, Messenger);RNA, 肿瘤(RNA, Neoplasm);受体, 雄激素(Receptors, Androgen);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)

DOI 10.1158/0008-5472.CAN-18-3965

PMID 31431456

发布时间 2020-06-01

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SF3B2-Mediated RNA Splicing Drives Human Prostate Cancer Progression.

Cancer research

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SF3B2-Mediated RNA Splicing Drives Human Prostate Cancer Progression.

Cancer research

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Cancer research

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