换一批Insoluble Aβ overexpression in an <i>App</i> knock-in mouse model alters microstructure and gamma oscillations in the prefrontal cortex, affecting anxiety-related behaviours.
第一作者：
Eleftheria,Pervolaraki
第一单位：
School of Biomedical Sciences, University of Leeds, Leeds, LS2 9JT, UK.
作者：
医学主题词
淀粉样β肽类(Amyloid beta-Peptides);淀粉样β蛋白前体(Amyloid beta-Protein Precursor);动物(Animals);各向异性(Anisotropy);焦虑(Anxiety);行为, 动物(Behavior, Animal);疾病模型, 动物(Disease Models, Animal);女(雌)性(Female);基因表达调控(Gene Expression Regulation);基因敲入技术(Gene Knock-In Techniques);男(雄)性(Male);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 转基因(Mice, Transgenic);N-甲基天冬氨酸(N-Methylaspartate);额叶前皮质(Prefrontal Cortex);受体, N-甲基-D-天冬氨酸(Receptors, N-Methyl-D-Aspartate);社会行为(Social Behavior);溶解度(Solubility);作业完成和分析(Task Performance and Analysis)
DOI
10.1242/dmm.040550
PMID
31439589
发布时间
2025-05-30
基金项目
WT_/Wellcome Trust/United Kingdom
EP-C-15-008/EPA/EPA/United States
BB/M008975/1/BB_/Biotechnology and Biological Sciences Research Council/United Kingdom
- 浏览59
相似文献
- 中文期刊
- 外文期刊
- 学位论文
- 会议论文
