Diversity of astacin-like metalloproteases identified by transcriptomic analysis in Peruvian Loxosceles laeta spider venom and in vitro activity characterization.

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作者： Raíssa,Medina-Santos ^[1] ; Clara,Guerra-Duarte ^[2] ; Sabrina,de Almeida Lima ^[3] ; Fernanda,Costal-Oliveira ^[3] ; Priscilla,Alves de Aquino ^[3] ; Anderson,Oliveira do Carmo ^[4] ; César Bonilla,Ferreyra ^[5] ; Edgar E,Gonzalez-Kozlova ^[3] ; Evanguedes,Kalapothakis ^[4] ; Carlos,Chávez-Olórtegui ^[6]

作者单位： Biochemistry and Immunology Department, Federal University of Minas Gerais, Brazil; Genetic, Ecology and Evolution Department, Federal University of Minas Gerais, Brazil. ^[1] Ezequiel Dias Foundation, Minas Gerais, Brazil. ^[2] Biochemistry and Immunology Department, Federal University of Minas Gerais, Brazil. ^[3] Genetic, Ecology and Evolution Department, Federal University of Minas Gerais, Brazil. ^[4] Univesidad Nacional Mayor de San Marcos, Facultad de Odontología, Lima, Peru; Instituto Nacional de Salud, Lima, Peru. ^[5] Biochemistry and Immunology Department, Federal University of Minas Gerais, Brazil. Electronic address: olortegi@icb.ufmg.br. ^[6]

关键词 LALP Loxosceles astacin-like metalloproteases Loxosceles laeta Metalloprotease Spider venom Transcriptome