Treatment with DNases rescues hidden neutrophil elastase from aggregated NETs.

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第一作者： Malgorzata J,Podolska

第一单位： Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Department of Internal Medicine 3-Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlange, Germany.

作者： Malgorzata J,Podolska ^[1] ; Aparna,Mahajan ^[1] ; Jonas,Hahn ^[1] ; Jasmin,Knopf ^[1] ; Christian,Maueröder ^[1] ; Lenka,Petru ^[2] ; Marc,Ullmann ^[3] ; Georg,Schett ^[1] ; Moritz,Leppkes ^[4] ; Martin,Herrmann ^[1] ; Luis E,Muñoz ^[1] ; Christine,Schauer ^[5]

作者单位： Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Department of Internal Medicine 3-Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlange, Germany. ^[1] Cell Clearance in Health and Disease Lab, VIB Center for Inflammation Research, Ghent, Belgium. ^[2] Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium. ^[3] Department of Rheumatology, First Faculty of Medicine, Charles University-Institute of Rheumatology, Prague, Czech Republic. ^[4] Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Department of Internal Medicine 1-Gastroenterology, Pneumology and Endocrinology, Universitätsklinikum Erlangen, Erlangen, Germany. ^[5]

关键词 DNase?1 NETs aggregated NETs neutrophil elastase neutrophils