Modulating Pathogenesis with Mobile-CRISPRi.

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第一作者： Jiuxin,Qu

第一单位： Chan Zuckerberg Biohub, San Francisco, California, USA.;Department of Medicine, University of California, San Francisco, San Francisco, California, USA.

作者： Jiuxin,Qu ^[1] ; Neha K,Prasad ^[1] ; Michelle A,Yu ^[2] ; Shuyan,Chen ^[1] ; Amy,Lyden ^[3] ; Nadia,Herrera ^[1] ; Melanie R,Silvis ^[4] ; Emily,Crawford ^[5] ; Mark R,Looney ^[2] ; Jason M,Peters ^[6] ; Oren S,Rosenberg ^[7]

作者单位： Chan Zuckerberg Biohub, San Francisco, California, USA.;Department of Medicine, University of California, San Francisco, San Francisco, California, USA. ^[1] Department of Medicine, University of California, San Francisco, San Francisco, California, USA. ^[2] Chan Zuckerberg Biohub, San Francisco, California, USA. ^[3] Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, USA. ^[4] Chan Zuckerberg Biohub, San Francisco, California, USA.;Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, USA. ^[5] Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, USA jpeters2@wisc.edu oren.rosenberg@ucsf.edu. ^[6] Chan Zuckerberg Biohub, San Francisco, California, USA jpeters2@wisc.edu oren.rosenberg@ucsf.edu.;Department of Medicine, University of California, San Francisco, San Francisco, California, USA. ^[7]

关键词 CRISPRi Pseudomonas aeruginosa conditionally essential genes infection model type III secretion virulence lifestyle genes