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MicroRNA-34a Regulates the Depression-like Behavior in Mice by Modulating the Expression of Target Genes in the Dorsal Raphè.

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第一作者： Luisa,Lo Iacono

第一单位： Department of Psychology, Sapienza University, Via Dei Marsi, 78, 00184, Rome, Italy.;IRCCS Santa Lucia Foundation, Via del Fosso di Fiorano, 64, 00143, Rome, Italy.

作者： Luisa,Lo Iacono ^[1] ; Donald,Ielpo ^[2] ; Alessandra,Accoto ^[3] ; Matteo,Di Segni ^[1] ; Lucy,Babicola ^[4] ; Sebastian Luca,D'Addario ^[2] ; Fabio,Ferlazzo ^[3] ; Tiziana,Pascucci ^[1] ; Rossella,Ventura ^[5] ; Diego,Andolina ^[6]

作者单位： Department of Psychology, Sapienza University, Via Dei Marsi, 78, 00184, Rome, Italy.;IRCCS Santa Lucia Foundation, Via del Fosso di Fiorano, 64, 00143, Rome, Italy. ^[1] Department of Psychology, Sapienza University, Via Dei Marsi, 78, 00184, Rome, Italy.;Behavioral Neuroscience PhD Programme, Sapienza University, Piazzale Aldo Moro 5, 00184, Rome, Italy. ^[2] Department of Psychology, Sapienza University, Via Dei Marsi, 78, 00184, Rome, Italy. ^[3] Department of Applied and Biotechnological Clinical Sciences, University of L'Aquila, 67010, L'Aquila, Italy. ^[4] Department of Psychology, Sapienza University, Via Dei Marsi, 78, 00184, Rome, Italy. rossella.ventura@uniroma1.it.;IRCCS Santa Lucia Foundation, Via del Fosso di Fiorano, 64, 00143, Rome, Italy. rossella.ventura@uniroma1.it. ^[5] Department of Psychology, Sapienza University, Via Dei Marsi, 78, 00184, Rome, Italy. diego.andolina@uniroma1.it.;IRCCS Santa Lucia Foundation, Via del Fosso di Fiorano, 64, 00143, Rome, Italy. diego.andolina@uniroma1.it. ^[6]

关键词 Ago2, RISC-Seq Chronic stress Depression-like behavior MicroRNA-34 Raphe nuclei Serotonin