首页> The Journal of biological chemistry> Matrix-degrading protease ADAMTS-5 cleaves inter-α-inhibitor and releases active heavy chain 2 in synovial fluids from arthritic patients.

Matrix-degrading protease ADAMTS-5 cleaves inter-α-inhibitor and releases active heavy chain 2 in synovial fluids from arthritic patients.

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第一作者： Carsten,Scavenius

第一单位： Department of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus, Denmark.

作者： Carsten,Scavenius ^[1] ; Emil Christian,Poulsen ^[1] ; Ida B,Thøgersen ^[1] ; Margaret,Roebuck ^[2] ; Simon,Frostick ^[2] ; George,Bou-Gharios ^[3] ; Kazuhiro,Yamamoto ^[3] ; Bent,Deleuran ^[4] ; Jan J,Enghild ^[5]

作者单位： Department of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus, Denmark. ^[1] Department of Molecular and Clinical Medicine, University of Liverpool, Liverpool L69 3BX, United Kingdom. ^[2] Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool L7 8TX, United Kingdom. ^[3] Department of Biomedicine, Aarhus University, 8000 Aarhus, Denmark.;Department of Rheumatology, Aarhus University Hospital, 8200 Aarhus, Denmark. ^[4] Department of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus, Denmark jje@mbg.au.dk. ^[5]

关键词 ADAMTS arthritis bikunin extracellular matrix protein hyaluronan inter-α-inhibitor metalloprotease