Effect of Metformin Plus Tyrosine Kinase Inhibitors Compared With Tyrosine Kinase Inhibitors Alone in Patients With Epidermal Growth Factor Receptor-Mutated Lung Adenocarcinoma: A Phase 2 Randomized Clinical Trial.

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作者： Oscar,Arrieta ^[1] ; Feliciano,Barrón ^[1] ; Miguel-Ángel Salinas,Padilla ^[1] ; Alejandro,Avilés-Salas ^[1] ; Laura Alejandra,Ramírez-Tirado ^[1] ; Manuel Jesús,Arguelles Jiménez ^[1] ; Edgar,Vergara ^[1] ; Zyanya Lucia,Zatarain-Barrón ^[1] ; Norma,Hernández-Pedro ^[1] ; Andrés F,Cardona ^[2] ; Graciela,Cruz-Rico ^[3] ; Pedro,Barrios-Bernal ^[4] ; Masao,Yamamoto Ramos ^[1] ; Rafael,Rosell ^[1]

作者单位： Thoracic Oncology Unit, Instituto Nacional de Cancerología (INCan), Mexico City, Mexico. ^[1] Clinical and Translational Oncology Group, Clínica del Country, Bogotá, Colombia. ^[2] Foundation for Clinical and Applied Cancer Research (FICMAC), Bogotá, Colombia. ^[3] Clinical Research and Biology Systems Department, Universidad el Bosque, Bogotá, Colombia. ^[4] Department of Radiology and Imaging, Instituto Nacional de Cancerología (INCan), Mexico City, Mexico. ^[5] Catalan Institute of Oncology, Germans Trias i Pujol Research Institute and Hospital Campus Can Ruti, Barcelona, Spain. ^[6]

DOI 10.1001/jamaoncol.2019.2553

PMID 31486833

发布时间 2023-10-13

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JAMA oncology

2019年5卷11期

e192553页

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Effect of Metformin Plus Tyrosine Kinase Inhibitors Compared With Tyrosine Kinase Inhibitors Alone in Patients With Epidermal Growth Factor Receptor-Mutated Lung Adenocarcinoma: A Phase 2 Randomized Clinical Trial.

JAMA oncology

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JAMA oncology

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Effect of Metformin Plus Tyrosine Kinase Inhibitors Compared With Tyrosine Kinase Inhibitors Alone in Patients With Epidermal Growth Factor Receptor-Mutated Lung Adenocarcinoma: A Phase 2 Randomized Clinical Trial.

JAMA oncology

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JAMA oncology

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