Progranulin promotes melanoma progression by inhibiting natural killer cell recruitment to the tumor microenvironment.

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作者： Ramouna,Voshtani ^[1] ; Mei,Song ^[2] ; Huan,Wang ^[1] ; Xiaoqi,Li ^[1] ; Wei,Zhang ^[3] ; Mojdeh S,Tavallaie ^[4] ; Wenjun,Yan ^[1] ; Joseph,Sun ^[5] ; Fang,Wei ^[6] ; Xiaojing,Ma ^[7]

作者单位： State Key Laboratory of Microbial Metabolism, Sheng Yushou Center of Cell Biology and Immunology, School of Life Science and Biotechnology, Shanghai Jiaotong University, Shanghai, China. ^[1] Department of Microbiology and Immunology, Weill Cornell Medicine, New York, USA. ^[2] State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China. ^[3] Department of Pharmaceutical Sciences, Shanghai Jiaotong University, Shanghai, 200240, China. ^[4] Immunology Program, Memorial Sloan-Kettering Cancer Center, New York, USA. ^[5] State Key Laboratory of Microbial Metabolism, Sheng Yushou Center of Cell Biology and Immunology, School of Life Science and Biotechnology, Shanghai Jiaotong University, Shanghai, China. Electronic address: fangwei@sjtu.edu.cn. ^[6] State Key Laboratory of Microbial Metabolism, Sheng Yushou Center of Cell Biology and Immunology, School of Life Science and Biotechnology, Shanghai Jiaotong University, Shanghai, China; Department of Microbiology and Immunology, Weill Cornell Medicine, New York, USA. Electronic address: xim2002@sjtu.edu.cn. ^[7]

关键词 CCL5 Immune response Melanoma Natural killer cell Progranulin