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首页> Scientific reports> TRAF3 regulates the oncogenic proteins Pim2 and c-Myc to restrain survival in normal and malignant B cells.

TRAF3 regulates the oncogenic proteins Pim2 and c-Myc to restrain survival in normal and malignant B cells.

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作者： Amy L,Whillock ^[1] ; Nurbek,Mambetsariev ^[2] ; Wai W,Lin ^[3] ; Laura L,Stunz ^[4] ; Gail A,Bishop ^[1]

作者单位： Department of Microbiology & Immunology, University of Iowa, Iowa City, IA, USA. ^[1] Immunology Graduate Program, University of Iowa, Iowa City, IA, USA. ^[2] Medical Scientist Training Program, University of Iowa, Iowa City, IA, USA. ^[3] Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA. ^[4] Northwestern Memorial Hospital, Chicago, IL, USA. ^[5] Sanford-Burnham-Prebys Medical Discovery Institute, La Jolla, CA, USA. ^[6] Department of Microbiology & Immunology, University of Iowa, Iowa City, IA, USA. gail-bishop@uiowa.edu. ^[7] Internal Medicine, University of Iowa, Iowa City, IA, USA. gail-bishop@uiowa.edu. ^[8] Immunology Graduate Program, University of Iowa, Iowa City, IA, USA. gail-bishop@uiowa.edu. ^[9] Medical Scientist Training Program, University of Iowa, Iowa City, IA, USA. gail-bishop@uiowa.edu. ^[10] Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA, USA. gail-bishop@uiowa.edu. ^[11] VA Medical Center, Iowa City, IA, USA. gail-bishop@uiowa.edu. ^[12]

主题词动物(Animals);B-淋巴细胞(B-Lymphocytes);细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);小鼠(Mice);磷酰化(Phosphorylation);原癌基因蛋白质类(Proto-Oncogene Proteins);原癌基因蛋白质c-myc(Proto-Oncogene Proteins c-myc);STAT3转录因子(STAT3 Transcription Factor);TNF受体相关因子3(TNF Receptor-Associated Factor 3)

DOI 10.1038/s41598-019-49390-9

PMID 31501481

发布时间 2021-12-04

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Scientific reports

Scientific reports

2019年9卷1期

12884页

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