首页> Alzheimer's & dementia : the journal of the Alzheimer's Association> Genetic resilience to Alzheimer's disease in APOE ε4 homozygotes: A systematic review.

Genetic resilience to Alzheimer's disease in APOE ε4 homozygotes: A systematic review.

导出原文传递

翻译打印收藏纠错

第一作者： Aamira J,Huq

第一单位： Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Department of Genomic Medicine, Royal Melbourne Hospital, Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Melbourne, VIC, Australia. Electronic address: Aamira.Huq@mh.org.au.

作者： Aamira J,Huq ^[1] ; Peter,Fransquet ^[2] ; Simon M,Laws ^[3] ; Joanne,Ryan ^[2] ; Robert,Sebra ^[4] ; Colin L,Masters ^[5] ; Ingrid M,Winship ^[6] ; Paul A,James ^[6] ; Paul,Lacaze ^[2]

作者单位： Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia; Department of Genomic Medicine, Royal Melbourne Hospital, Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Melbourne, VIC, Australia. Electronic address: Aamira.Huq@mh.org.au. ^[1] Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia. ^[2] Collaborative Genomics Group, Centre of Excellence for Alzheimer's Disease Research and Care, School of Medical and Health Sciences, Edith Cowan University, Joondalup, Western Australia, Australia; School of Pharmacy and Biomedical Sciences, Faculty of Health Sciences, Curtin Health Innovation Research Institute, Curtin University, Bentley, WA, Australia. ^[3] Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ^[4] The Florey Institute, University of Melbourne, Parkville, Victoria, Australia. ^[5] Department of Genomic Medicine, Royal Melbourne Hospital, Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Melbourne, VIC, Australia. ^[6]

关键词 APOE e4 homozygotes Alzheimer's disease CASP7 Genetic resilience Resilience SERPINA3

医学主题词等位基因(Alleles);阿尔茨海默病(Alzheimer Disease);载脂蛋白E4(Apolipoprotein E4);纯合子(Homozygote);人类(Humans);多态性, 单核苷酸(Polymorphism, Single Nucleotide);危险因素(Risk Factors)

DOI 10.1016/j.jalz.2019.05.011

PMID 31506248

发布时间 2020-09-02

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交