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Cell-specific image-guided transcriptomics identifies complex injuries caused by ischemic acute kidney injury in mice.

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第一作者： Tomoaki,Miyazaki

第一单位： 1Division of Nephrology, Department of Medicine, University of Washington, Seattle, WA 98195 USA.;2Division of Nephrology, Department of Medicine, Showa University, Yokohama, Japan.

作者： Tomoaki,Miyazaki ^[1] ; Sina A,Gharib ^[2] ; Yun-Wei A,Hsu ^[3] ; Katherine,Xu ^[4] ; Pavlo,Khodakivskyi ^[5] ; Akio,Kobayashi ^[3] ; Jason,Paragas ^[6] ; Alexander D,Klose ^[7] ; Kevin P,Francis ^[8] ; Elena,Dubikovskaya ^[5] ; Patrick S,Page-McCaw ^[9] ; Jonathan,Barasch ^[4] ; Neal,Paragas ^[3]

作者单位： 1Division of Nephrology, Department of Medicine, University of Washington, Seattle, WA 98195 USA.;2Division of Nephrology, Department of Medicine, Showa University, Yokohama, Japan. ^[1] 3Computational Medicine Core, Center for Lung Biology, University of Washington, Seattle, WA 98195 USA. ^[2] 1Division of Nephrology, Department of Medicine, University of Washington, Seattle, WA 98195 USA. ^[3] 4Renal Division, Department of Medicine, Columbia University, New York, NY 10027 USA. ^[4] 5Institute of Chemical Sciences and Engineering, Swiss Federal Institute of Technology of Lausanne (EPFL), Lausanne, Switzerland. ^[5] Lawrence Livermore Labs, Livermore, CA 94550 USA. ^[6] 7InVivo Analytics, Inc., New York, NY 10023 USA. ^[7] 8PerkinElmer, Inc., Hopkinton, MA 01748 USA. ^[8] 9Division of Nephrology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 USA. ^[9]

关键词 Bioluminescence imaging Gene expression analysis

医学主题词急性肾损伤(Acute Kidney Injury);动物(Animals);抗氧化剂(Antioxidants);成像, 三维(Imaging, Three-Dimensional);缺血(Ischemia);肾小管, 集合(Kidney Tubules, Collecting);小鼠, 近交C57BL(Mice, Inbred C57BL);肾单位(Nephrons);氧化性应激(Oxidative Stress);活性氧(Reactive Oxygen Species);再灌注损伤(Reperfusion Injury)

DOI 10.1038/s42003-019-0571-7

PMID 31508501

发布时间 2024-02-29

基金项目

K99 DK094873/DK/NIDDK NIH HHS/United States P30 DK017047/DK/NIDDK NIH HHS/United States P30 DK089507/DK/NIDDK NIH HHS/United States R00 DK094873/DK/NIDDK NIH HHS/United States

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Communications biology

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Cell-specific image-guided transcriptomics identifies complex injuries caused by ischemic acute kidney injury in mice.

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Cell-specific image-guided transcriptomics identifies complex injuries caused by ischemic acute kidney injury in mice.

Communications biology

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