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Magnesium supplementation therapy to prevent cisplatin-induced acute nephrotoxicity in pediatric cancer: A protocol for a randomized phase 2 trial.

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第一作者： Atsushi,Makimoto

第一单位： Department of Hematology / Oncology, Tokyo Metropolitan Children's Medical Center, 2-8-29, Musashidai, Fuchu-shi, Tokyo, 183-8561, Japan.;Clinical Trial Support Center, Tokyo Metropolitan Children's Medical Center, 2-8-29, Musashidai, Fuchu-shi, Tokyo, 183-8561, Japan.

作者： Atsushi,Makimoto ^[1] ; Motohiro,Matsui ^[2] ; Motoaki,Chin ^[3] ; Katsuyoshi,Koh ^[4] ; Masako,Tomotsune ^[5] ; Tetsuji,Kaneko ^[5] ; Yoshihiko,Morikawa ^[5] ; Yuki,Yuza ^[2]

作者单位： Department of Hematology / Oncology, Tokyo Metropolitan Children's Medical Center, 2-8-29, Musashidai, Fuchu-shi, Tokyo, 183-8561, Japan.;Clinical Trial Support Center, Tokyo Metropolitan Children's Medical Center, 2-8-29, Musashidai, Fuchu-shi, Tokyo, 183-8561, Japan. ^[1] Department of Hematology / Oncology, Tokyo Metropolitan Children's Medical Center, 2-8-29, Musashidai, Fuchu-shi, Tokyo, 183-8561, Japan. ^[2] Department of Pediatrics, Nihon University School of Medicine, 30-1, Ohyaguchi-kamicho, Itabashi-ku, Tokyo, 173-8610, Japan. ^[3] Department of Hematology / Oncology, Saitama Children's Medical Center, 1-2, Shin-toshin, Chuo-ku, Saitama-shi, Saitama, 330-8777, Japan. ^[4] Clinical Trial Support Center, Tokyo Metropolitan Children's Medical Center, 2-8-29, Musashidai, Fuchu-shi, Tokyo, 183-8561, Japan. ^[5]

关键词 B2M, beta-2 microglobrin CIN, cisplatin-induced nephrotoxicity Cisplatin GFR, glomerular filtration rate L-FABP, L-type fatty acid binding protein Magnesium Mg, magnesium NAG, N-acetyl-β-d-glucosaminidase NGAL, neutrophil gelatinase-associated lipocalin Nephrotoxicity Pediatric cancer

DOI 10.1016/j.conctc.2019.100440

PMID 31508533

发布时间 2023-10-13

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Contemporary clinical trials communications

2019年16卷

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Contemporary clinical trials communications

2019年16卷

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Magnesium supplementation therapy to prevent cisplatin-induced acute nephrotoxicity in pediatric cancer: A protocol for a randomized phase 2 trial.

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Magnesium supplementation therapy to prevent cisplatin-induced acute nephrotoxicity in pediatric cancer: A protocol for a randomized phase 2 trial.

Contemporary clinical trials communications

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Contemporary clinical trials communications

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