Intrinsic adriamycin resistance in p53-mutated breast cancer is related to the miR-30c/FANCF/REV1-mediated DNA damage response.
第一作者:
Shu,Lin
第一单位:
Department of Pharmacology, School of Pharmacy, China Medical University, No. 77 Puhe Road, Shenyang North New Area, 110122, Shenyang City, Liaoning, China.;Liaoning Key Laboratory of molecular targeted anti-tumor drug development and evaluation, China Medical University, No.77 Puhe Road, Shenyang North New Area, 110122, Shenyang City, Liaoning, China.
作者:
医学主题词
3'非翻译区(3' Untranslated Regions);动物(Animals);抗生素类, 抗肿瘤(Antibiotics, Antineoplastic);乳腺肿瘤(Breast Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);细胞存活(Cell Survival);DNA损伤(DNA Damage);多柔比星(Doxorubicin);抗药性, 肿瘤(Drug Resistance, Neoplasm);范可尼贫血互补群蛋白质F(Fanconi Anemia Complementation Group F Protein);女(雌)性(Female);人类(Humans);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 裸(Mice, Nude);微RNAs(MicroRNAs);突变(Mutation);核苷酸基转移酶类(Nucleotidyltransferases);移植, 异种(Transplantation, Heterologous);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53)
DOI
10.1038/s41419-019-1871-z
PMID
31511498
发布时间
2022-01-26
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