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Conversion of Sox2-dependent Merkel cell carcinoma to a differentiated neuron-like phenotype by T antigen inhibition.

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第一作者： Alexis,Harold

第一单位： Cancer Virology Program, Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, PA 15213.

作者： Alexis,Harold ^[1] ; Yutaka,Amako ^[2] ; Junichi,Hachisuka ^[3] ; Yulong,Bai ^[4] ; Meng Yen,Li ^[5] ; Linda,Kubat ^[6] ; Jan,Gravemeyer ^[6] ; Jonathan,Franks ^[7] ; Julia R,Gibbs ^[1] ; Hyun Jung,Park ^[4] ; Elena,Ezhkova ^[5] ; Jürgen C,Becker ^[6] ; Masahiro,Shuda ^[8]

作者单位： Cancer Virology Program, Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, PA 15213. ^[1] Cancer Virology Program, Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, PA 15213.;Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA 15219. ^[2] Pittsburgh Center for Pain Research, University of Pittsburgh, Pittsburgh, PA 15213.;Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA 15213. ^[3] Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA 15260. ^[4] The Tisch Cancer Institute, Black Family Stem Cell Institute, Department of Cell, Developmental, and Regenerative Biology, Icahn School of Medicine at Mount Sinai, New York, NY 10029. ^[5] Translational Skin Cancer Research, Dermatology, German Cancer Consortium (DKTK), 45141 Essen, Germany. ^[6] Center for Biologic Imaging, University of Pittsburgh, Pittsburgh, PA 15261. ^[7] Cancer Virology Program, Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, PA 15213; mas253@pitt.edu.;Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA 15219. ^[8]

关键词 Atoh1 Merkel cell carcinoma Merkel cell polyomavirus Sox2 phenotypic conversion