PNPLA3 rs738409 G allele carriers with genotype 1b HCV cirrhosis have lower viral load but develop liver failure at younger age.
第一作者:
Renata,Senkerikova
第一单位:
Department of Hepatogastroenterology, Transplant Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
作者:
主题词
等位基因(Alleles);癌, 肝细胞(Carcinoma, Hepatocellular);病例对照研究(Case-Control Studies);横断面研究(Cross-Sectional Studies);女(雌)性(Female);疾病遗传易感性(Genetic Predisposition to Disease);基因型(Genotype);丙型肝炎, 慢性(Hepatitis C, Chronic);人类(Humans);脂肪酶(Lipase);肝(Liver);肝硬化(Liver Cirrhosis);肝功能衰竭(Liver Failure);肝肿瘤(Liver Neoplasms);肝移植(Liver Transplantation);男(雄)性(Male);膜蛋白质类(Membrane Proteins);中年人(Middle Aged);多态性, 单核苷酸(Polymorphism, Single Nucleotide);回顾性研究(Retrospective Studies);病毒载量(Viral Load)
DOI
10.1371/journal.pone.0222609
PMID
31527889
发布时间
2020-03-05
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PloS one
e0222609页
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