Safety and pharmacokinetics of dolutegravir in pregnant mothers with HIV infection and their neonates: A randomised trial (DolPHIN-1 study).-论文-万方医学网

第一作者： Catriona,Waitt

第一单位： Department of Molecular & Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.;Infectious Disease Institute, Makerere University College of Health Sciences, Kampala, Uganda.;Royal Liverpool University Hospital, Liverpool, United Kingdom.

作者： Catriona,Waitt ^[1] ; Catherine,Orrell ^[2] ; Stephen,Walimbwa ^[3] ; Yashna,Singh ^[2] ; Kenneth,Kintu ^[3] ; Bryony,Simmons ^[4] ; Julian,Kaboggoza ^[3] ; Mary,Sihlangu ^[2] ; Julie-Anne,Coombs ^[2] ; Thoko,Malaba ^[5] ; Josaphat,Byamugisha ^[6] ; Alieu,Amara ^[7] ; Joshua,Gini ^[7] ; Laura,Else ^[7] ; Christie,Heiburg ^[2] ; Eva Maria,Hodel ^[7] ; Helen,Reynolds ^[7] ; Ushma,Mehta ^[5] ; Pauline,Byakika-Kibwika ^[3] ; Andrew,Hill ^[7] ; Landon,Myer ^[5] ; Mohammed,Lamorde ^[3] ; Saye,Khoo ^[8]

作者单位： Department of Molecular & Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.;Infectious Disease Institute, Makerere University College of Health Sciences, Kampala, Uganda.;Royal Liverpool University Hospital, Liverpool, United Kingdom. ^[1] Desmond Tutu HIV Foundation, Cape Town, South Africa. ^[2] Infectious Disease Institute, Makerere University College of Health Sciences, Kampala, Uganda. ^[3] Department of Medicine, Imperial College London, London, United Kingdom. ^[4] Division of Epidemiology and Biostatistics and Centre for Infectious Diseases Epidemiology & Research, School of Public Health & Family Medicine, University of Cape Town, Cape Town, South Africa. ^[5] Department of Obstetrics and Gynaecology, Makerere University College of Health Sciences, Kampala, Uganda. ^[6] Department of Molecular & Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom. ^[7] Department of Molecular & Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.;Royal Liverpool University Hospital, Liverpool, United Kingdom. ^[8]

医学主题词成年人(Adult);炔类(Alkynes);苯并恶嗪类(Benzoxazines);环丙烷类(Cyclopropanes);女(雌)性(Female);HIV(HIV);HIV感染(HIV Infections);HIV整合酶抑制剂(HIV Integrase Inhibitors);杂环化合物, 3环(Heterocyclic Compounds, 3-Ring);人类(Humans);婴儿, 新生(Infant, Newborn);传染性疾病传播, 垂直(Infectious Disease Transmission, Vertical);母体胎儿间交换(Maternal-Fetal Exchange);乳, 人(Milk, Human);恶嗪类(Oxazines);哌嗪类(Piperazines);妊娠(Pregnancy);吡啶酮类(Pyridones);逆转录酶抑制剂(Reverse Transcriptase Inhibitors);危险性评估(Risk Assessment);南非(South Africa);治疗结果(Treatment Outcome);乌干达(Uganda);病毒载量(Viral Load);青年人(Young Adult)

DOI 10.1371/journal.pmed.1002895

PMID 31539371

发布时间 2025-05-30

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Safety and pharmacokinetics of dolutegravir in pregnant mothers with HIV infection and their neonates: A randomised trial (DolPHIN-1 study).

PLoS medicine

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Safety and pharmacokinetics of dolutegravir in pregnant mothers with HIV infection and their neonates: A randomised trial (DolPHIN-1 study).

PLoS medicine

相似文献

同项目论文

PLoS medicine

相关期刊

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