Activation of Skeletal Stem and Progenitor Cells for Bone Regeneration Is Driven by PDGFRβ Signaling.

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第一作者： Anna-Marei,Böhm

第一单位： Laboratory of Skeletal Cell Biology and Physiology (SCEBP), Skeletal Biology and Engineering Research Center (SBE), Department of Development and Regeneration, KU Leuven, 3000 Leuven, Belgium.

作者： Anna-Marei,Böhm ^[1] ; Naomi,Dirckx ^[1] ; Robert J,Tower ^[1] ; Nicolas,Peredo ^[1] ; Sebastiaan,Vanuytven ^[2] ; Koen,Theunis ^[2] ; Elena,Nefyodova ^[1] ; Ruben,Cardoen ^[1] ; Volkhard,Lindner ^[3] ; Thierry,Voet ^[4] ; Matthias,Van Hul ^[1] ; Christa,Maes ^[5]

作者单位： Laboratory of Skeletal Cell Biology and Physiology (SCEBP), Skeletal Biology and Engineering Research Center (SBE), Department of Development and Regeneration, KU Leuven, 3000 Leuven, Belgium. ^[1] Laboratory of Reproductive Genomics, Department of Human Genetics, KU Leuven, 3000 Leuven, Belgium. ^[2] Center for Molecular Medicine, Maine Medical Center Research Institute, Scarborough, ME, USA. ^[3] Laboratory of Reproductive Genomics, Department of Human Genetics, KU Leuven, 3000 Leuven, Belgium; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge CB10 1SA, UK. ^[4] Laboratory of Skeletal Cell Biology and Physiology (SCEBP), Skeletal Biology and Engineering Research Center (SBE), Department of Development and Regeneration, KU Leuven, 3000 Leuven, Belgium. Electronic address: christa.maes@kuleuven.be. ^[5]

关键词 PDGF PDGF receptor blood vessels bone bone marrow stromal cells bone regeneration fracture repair osteoprogenitors pericytes skeletal stem cells