Chimeric antigen receptor modified T cell (CAR-T) co-expressed with ICOSL-41BB promote CAR-T proliferation and tumor rejection.

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作者： Wei,Hu ^[1] ; Xin,Huang ^[1] ; Xingyue,Huang ^[1] ; Wenwei,Chen ^[1] ; Lidan,Hao ^[1] ; Zubing,Chen ^[2]

作者单位： Department of Ultrasound, Renmin Hospital of Wuhan University, Jiefang Road 238, Wuhan, 430060, China. ^[1] Department of Hepatobiliary Surgery, Renmin Hospital of Wuhan University, Jiefang Road 238, Wuhan, 430060, China. Electronic address: chenzubing@aliyun.com. ^[2]

关键词 41BB CAR-T GPC3 HCC ICOSL PI3K

主题词细胞凋亡(Apoptosis);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);人类(Humans);免疫疗法, 过继(Immunotherapy, Adoptive);突变(Mutation);肿瘤(Neoplasms);表型(Phenotype);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);信号传导(Signal Transduction);T淋巴细胞(T-Lymphocytes)

DOI 10.1016/j.biopha.2019.109333

PMID 31545280

发布时间 2020-02-04

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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

2019年118卷

109333页

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Chimeric antigen receptor modified T cell (CAR-T) co-expressed with ICOSL-41BB promote CAR-T proliferation and tumor rejection.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

相似文献

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

相关期刊

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Chimeric antigen receptor modified T cell (CAR-T) co-expressed with ICOSL-41BB promote CAR-T proliferation and tumor rejection.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

相似文献

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

相关期刊

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