Co-occurring Alterations in the RAS-MAPK Pathway Limit Response to MET Inhibitor Treatment in MET Exon 14 Skipping Mutation-Positive Lung Cancer.

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第一作者： Julia K,Rotow

第一单位： Department of Medicine, University of California, San Francisco, California.;Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California.

作者： Julia K,Rotow ^[1] ; Philippe,Gui ^[1] ; Wei,Wu ^[1] ; Victoria M,Raymond ^[2] ; Richard B,Lanman ^[2] ; Frederic J,Kaye ^[3] ; Nir,Peled ^[4] ; Ferran,Fece de la Cruz ^[5] ; Brandon,Nadres ^[5] ; Ryan B,Corcoran ^[5] ; Iwei,Yeh ^[6] ; Boris C,Bastian ^[6] ; Petr,Starostik ^[7] ; Kimberly,Newsom ^[7] ; Victor R,Olivas ^[8] ; Alexander M,Wolff ^[9] ; James S,Fraser ^[9] ; Eric A,Collisson ^[1] ; Caroline E,McCoach ^[1] ; D Ross,Camidge ^[10] ; Jose,Pacheco ^[10] ; Lyudmila,Bazhenova ^[11] ; Tianhong,Li ^[12] ; Trever G,Bivona ^[13] ; Collin M,Blakely ^[13]

作者单位： Department of Medicine, University of California, San Francisco, California.;Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California. ^[1] Guardant Health, Inc., Redwood City, California. ^[2] Department of Medicine, University of Florida, Gainesville, Florida. ^[3] Soroka Medical Center, Ben-Gurion University, Beer-Sheva, Israel. ^[4] Massachusetts General Hospital Cancer Center and Department of Medicine, Harvard Medical School, Boston, Massachusetts. ^[5] Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California.;Departments of Dermatology and Pathology, and Clinical Cancer Genomics Laboratory, University of California, San Francisco, California. ^[6] Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, Florida. ^[7] Department of Medicine, University of California, San Francisco, California. ^[8] Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California. ^[9] University of Colorado, Aurora, Colorado. ^[10] University of California, San Diego, California. ^[11] Department of Internal Medicine, University of California, Davis, California. ^[12] Department of Medicine, University of California, San Francisco, California. Collin.blakely@ucsf.edu trever.bivona@ucsf.edu.;Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California. ^[13]