Human monocytic myeloid-derived suppressor cells impair B-cell phenotype and function in vitro.

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第一作者： Jennifer,Jaufmann

第一单位： Department of Pharmacology and Experimental Therapy, Institute of Experimental and Clinical Pharmacology and Toxicology and ICePhA, University of Tuebingen, Tuebingen, Germany.;Children's Hospital and Interdisciplinary Center for Infectious Diseases, University of Tuebingen, Tuebingen, Germany.

作者： Jennifer,Jaufmann ^[1] ; Felipe J N,Lelis ^[2] ; Annkathrin C,Teschner ^[3] ; Katja,Fromm ^[4] ; Nikolaus,Rieber ^[5] ; Dominik,Hartl ^[3] ; Sandra,Beer-Hammer ^[6]

作者单位： Department of Pharmacology and Experimental Therapy, Institute of Experimental and Clinical Pharmacology and Toxicology and ICePhA, University of Tuebingen, Tuebingen, Germany.;Children's Hospital and Interdisciplinary Center for Infectious Diseases, University of Tuebingen, Tuebingen, Germany. ^[1] Children's Hospital and Interdisciplinary Center for Infectious Diseases, University of Tuebingen, Tuebingen, Germany.;Department of Medicine, Division of Rheumatology, Immunology and Allergy Brigham and Women's Hospital and Harvard Medical School, 60 Fenwood Road, Boston, MA, USA. ^[2] Children's Hospital and Interdisciplinary Center for Infectious Diseases, University of Tuebingen, Tuebingen, Germany. ^[3] Children's Hospital and Interdisciplinary Center for Infectious Diseases, University of Tuebingen, Tuebingen, Germany.;Biozentrum, University of Basel, Infection Biology, Basel, Switzerland. ^[4] Children's Hospital and Interdisciplinary Center for Infectious Diseases, University of Tuebingen, Tuebingen, Germany.;Department of Pediatrics, Kinderklinik Muenchen Schwabing, Muenchen Klinik und Klinikum rechts der Isar, Technical University of Munich, Munich, Germany. ^[5] Department of Pharmacology and Experimental Therapy, Institute of Experimental and Clinical Pharmacology and Toxicology and ICePhA, University of Tuebingen, Tuebingen, Germany. ^[6]

关键词 B-cell phenotype B-cell responses Immune regulation Immune suppression Monocytic myeloid-derived suppressor cells

主题词 B-淋巴细胞(B-Lymphocytes);细胞增殖(Cell Proliferation);细胞, 培养的(Cells, Cultured);人类(Humans);淋巴细胞活化(Lymphocyte Activation);表型(Phenotype)

DOI 10.1002/eji.201948240

PMID 31557313

发布时间 2020-07-10

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