首页> Proceedings of the National Academy of Sciences of the United States of America> <i>Francisella novicida</i> Cas9 interrogates genomic DNA with very high specificity and can be used for mammalian genome editing.

<i>Francisella novicida</i> Cas9 interrogates genomic DNA with very high specificity and can be used for mammalian genome editing.

导出 OA

翻译打印收藏纠错

第一作者： Sundaram,Acharya

第一单位： Genomics and Molecular Medicine Unit, Council of Scientific and Industrial Research-Institute of Genomics & Integrative Biology, New Delhi, 110025, India.;Academy of Scientific & Innovative Research, Ghaziabad, 201002, India.

作者： Sundaram,Acharya ^[1] ; Arpit,Mishra ^[2] ; Deepanjan,Paul ^[2] ; Asgar Hussain,Ansari ^[1] ; Mohd,Azhar ^[1] ; Manoj,Kumar ^[1] ; Riya,Rauthan ^[1] ; Namrata,Sharma ^[2] ; Meghali,Aich ^[1] ; Dipanjali,Sinha ^[1] ; Saumya,Sharma ^[1] ; Shivani,Jain ^[2] ; Arjun,Ray ^[2] ; Suman,Jain ^[3] ; Sivaprakash,Ramalingam ^[1] ; Souvik,Maiti ^[4] ; Debojyoti,Chakraborty ^[5]

作者单位： Genomics and Molecular Medicine Unit, Council of Scientific and Industrial Research-Institute of Genomics & Integrative Biology, New Delhi, 110025, India.;Academy of Scientific & Innovative Research, Ghaziabad, 201002, India. ^[1] Genomics and Molecular Medicine Unit, Council of Scientific and Industrial Research-Institute of Genomics & Integrative Biology, New Delhi, 110025, India. ^[2] Kamala Hospital and Research Centre, Thalassemia and Sickle Cell Society, Rajendra Nagar, Hyderabad, 500052, India. ^[3] Genomics and Molecular Medicine Unit, Council of Scientific and Industrial Research-Institute of Genomics & Integrative Biology, New Delhi, 110025, India.;Academy of Scientific & Innovative Research, Ghaziabad, 201002, India.;Institute of Genomics and Integrative Biology (IGIB)-National Chemical Laboratory (NCL) Joint Center, Council of Scientific and Industrial Research-National Chemical Laboratory, Pune, 411008, India. ^[4] Genomics and Molecular Medicine Unit, Council of Scientific and Industrial Research-Institute of Genomics & Integrative Biology, New Delhi, 110025, India; debojyoti.chakraborty@igib.in.;Academy of Scientific & Innovative Research, Ghaziabad, 201002, India. ^[5]

关键词 CRISPR Cas9 gene therapy genome editing iPSCs sickle cell anemia