Recent BCR stimulation induces a negative autoregulatory loop via FBXO10 mediated degradation of HGAL.

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作者： Fengjie,Guo ^[1] ; Yuan,Luo ^[2] ; Xiaoyu,Jiang ^[1] ; XiaoQing,Lu ^[2] ; Domenico,Roberti ^[1] ; Chen,Lossos ^[2] ; Kranthi,Kunkalla ^[1] ; Marco,Magistri ^[2] ; Lixin,Rui ^[3] ; Ramiro,Verdun ^[1] ; Francisco,Vega ^[4] ; Vincent T,Moy ^[1] ; Izidore S,Lossos ^[2]

作者单位： Division of Hematology, Department of Medicine, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA. ^[1] Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL, USA. ^[2] Department of Pathology, Laura and Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, NY, USA. ^[3] Department of Pathology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, 33136, USA. ^[4] Department of Medicine and Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA. ^[5] Department of Physiology and Biophysics, University of Miami Miller School of Medicine, Miami, FL, USA. ^[6] Division of Hematology, Department of Medicine, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA. ILossos@med.miami.edu. ^[7] Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, Miami, FL, USA. ILossos@med.miami.edu. ^[8]