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首页> The Indian journal of medical research> Aspirin & clopidogrel non-responsiveness & its association with genetic polymorphisms in patients with myocardial infarction.

Aspirin & clopidogrel non-responsiveness & its association with genetic polymorphisms in patients with myocardial infarction.

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作者： Chandra Prakash,Pandey ^[1] ; Ankita,Misra ^[2] ; Mahendra Pal Singh,Negi ^[3] ; Babu Nageswararao,Kanuri ^[2] ; Yashpal Singh,Chhonker ^[4] ; Rabi Shanker,Bhatta ^[4] ; Varun Shanker,Narain ^[5] ; Madhu,Dikshit ^[2]

作者单位： Divisions of Pharmacology, CSIR-Central Drug Research Institute; Department of Cardiology, King George Medical University, Lucknow, India. ^[1] Divisions of Pharmacology, CSIR-Central Drug Research Institute, Lucknow, India. ^[2] Divisions of Toxicology & Experimental Medicine, CSIR-Central Drug Research Institute, Lucknow, India. ^[3] Divisions of Pharmaceutics & Pharmacokinetics, CSIR-Central Drug Research Institute, Lucknow, India. ^[4] Department of Cardiology, King George Medical University, Lucknow, India. ^[5]

关键词 Aspirin clopidogrel drug compliance myocardial infarction non-responders platelet activation platelet aggregation responders single-nucleotide polymorphism

主题词老年人(Aged);等位基因(Alleles);阿司匹林(Aspirin);CD40配体(CD40 Ligand);环氧化酶1(Cyclooxygenase 1);细胞色素P450酶系统(Cytochrome P-450 Enzyme System);女(雌)性(Female);遗传关联研究(Genetic Association Studies);疾病遗传易感性(Genetic Predisposition to Disease);基因型(Genotype);人类(Humans);男(雄)性(Male);中年人(Middle Aged);心肌梗死(Myocardial Infarction);血小板聚集抑制剂(Platelet Aggregation Inhibitors);血小板膜糖蛋白类(Platelet Membrane Glycoproteins);多态现象, 遗传(Polymorphism, Genetic);受体, 嘌呤能P2Y12(Receptors, Purinergic P2Y12);血栓烷B2(Thromboxane B2)

DOI 10.4103/ijmr.IJMR_782_17

PMID 31571629

发布时间 2020-04-08

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The Indian journal of medical research

The Indian journal of medical research

2019年150卷1期

50-61页

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