Mass Spectrometry-Based Plasma Proteomics: Considerations from Sample Collection to Achieving Translational Data.

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第一作者： Vera,Ignjatovic

第一单位： Haematology Research , Murdoch Children's Research Institute , Parkville , VIC 3052 , Australia.;Department of Paediatrics , The University of Melbourne , Parkville , VIC 3052 , Australia.

作者： Vera,Ignjatovic ^[1] ; Philipp E,Geyer ^[2] ; Krishnan K,Palaniappan ^[3] ; Jessica E,Chaaban ^[4] ; Gilbert S,Omenn ^[5] ; Mark S,Baker ^[6] ; Eric W,Deutsch ^[7] ; Jochen M,Schwenk ^[8]

作者单位： Haematology Research , Murdoch Children's Research Institute , Parkville , VIC 3052 , Australia.;Department of Paediatrics , The University of Melbourne , Parkville , VIC 3052 , Australia. ^[1] NNF Center for Protein Research, Faculty of Health Sciences , University of Copenhagen , 2200 Copenhagen , Denmark.;Department of Proteomics and Signal Transduction , Max Planck Institute of Biochemistry , 82152 Martinsried , Germany. ^[2] Freenome , 259 East Grand Avenue , South San Francisco , California 94080 , United States. ^[3] Haematology Research , Murdoch Children's Research Institute , Parkville , VIC 3052 , Australia. ^[4] Departments of Computational Medicine & Bioinformatics, Human Genetics, and Internal Medicine and School of Public Health , University of Michigan , 100 Washtenaw Avenue , Ann Arbor , Michigan 48109-2218 , United States. ^[5] Department of Biomedical Sciences, Faculty of Medicine & Health Sciences , Macquarie University , 75 Talavera Road , North Ryde , NSW 2109 , Australia. ^[6] Institute for Systems Biology , 401 Terry Avenue North , Seattle , Washington 98109 , United States. ^[7] Affinity Proteomics, SciLifeLab , KTH Royal Institute of Technology , 171 65 Stockholm , Sweden. ^[8]

关键词 Human Plasma Proteome Project (HPPP)Human Proteome Project (HPP)bioinformatic analysis blood data acquisition data processing mass spectrometry (MS)plasma plasma processing workflows quality metrics sample collection serum study design