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Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy.

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第一作者: Kathrin,Renner
第一单位: Department of Internal Medicine III, University Hospital Regensburg, Regensburg, Germany; Regensburg Center for Interventional Immunology, Regensburg, Germany. Electronic address: kathrin.renner-sattler@ukr.de.
作者单位: Department of Internal Medicine III, University Hospital Regensburg, Regensburg, Germany; Regensburg Center for Interventional Immunology, Regensburg, Germany. Electronic address: kathrin.renner-sattler@ukr.de. [1] Department of Internal Medicine III, University Hospital Regensburg, Regensburg, Germany. [2] Department of Surgery, University Hospital Regensburg, Regensburg, Germany. [3] Division of General Zoology, University of Kaiserslautern, Kaiserslautern, Germany. [4] Regensburg Center for Interventional Immunology, Regensburg, Germany. [5] Institute for Immunology, University Medical Center Johannes Gutenberg University (UMC) Mainz, Mainz, Germany. [6] Institute of Pathology, University of Regensburg, Regensburg, Germany. [7] Institute of Organic Chemistry, University of Regensburg, Regensburg, Germany. [8] Department Medical Oncology and Division of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, the Netherlands. [9] Department of Nuclear Medicine, University Medical Center, Johannes Gutenberg University Mainz, Mainz, Germany. [10] Institute of Research on Cancer and Aging (IRCAN), CNRS-INSERM-UNS UMR 7284, Nice, France. [11] Institute of Research on Cancer and Aging (IRCAN), CNRS-INSERM-UNS UMR 7284, Nice, France; Department of Medical Biology, Scientific Centre of Monaco (CSM), Monaco. [12] Department of Chemistry, The Scripps Research Institute, Scripps-Florida, Jupiter, FL, USA. [13] NanoString Technologies, Seattle, WA, USA. [14] Department of General and Visceral Surgery, Medical Center, Faculty of Medicine University of Freiburg, Freiburg, Germany. [15] Institute for Immunology, University Medical Center Johannes Gutenberg University (UMC) Mainz, Mainz, Germany; Research Center for Immunotherapy (FZI), UMC Mainz, Mainz, Germany; University Cancer Center Mainz, UMC Mainz, Mainz, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany. [16] Department of Tumor Biology, Moffitt Cancer Center and Research Institute, Tampa, FL, USA. [17] Institute of Functional Genomics, University of Regensburg, Regensburg, Germany. [18] Bristol-Myers Squibb, Redwood City, CA, USA. [19] Department of Internal Medicine III, University Hospital Regensburg, Regensburg, Germany; Regensburg Center for Interventional Immunology, Regensburg, Germany. [20]
DOI 10.1016/j.celrep.2019.08.068
PMID 31577944
发布时间 2020-09-17
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