Double knock-out of Hmga1 and Hipk2 genes causes perinatal death associated to respiratory distress and thyroid abnormalities in mice.
第一作者:
Raffaele,Gerlini
第一单位:
Department of Molecular Medicine and Medical Biotechnology, University of Naples, Naples, Italy.;Institute of Experimental Genetics, Helmholtz Zentrum, Munich, Germany.
作者:
医学主题词
动物(Animals);动物, 新生(Animals, Newborn);胚胎发育(Embryonic Development);基因缺失(Gene Deletion);基因表达调控(Gene Expression Regulation);HMGA1a蛋白(HMGA1a Protein);人类(Humans);肺(Lung);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);肺表面活性物质相关蛋白质类(Pulmonary Surfactant-Associated Proteins);呼吸道疾病(Respiratory Tract Diseases);甲状腺(Thyroid Gland)
DOI
10.1038/s41419-019-1975-5
PMID
31582725
发布时间
2021-12-04
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