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Cell Type Purification by Single-Cell Transcriptome-Trained Sorting.

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第一作者： Chloé S,Baron

第一单位： Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center, Utrecht, the Netherlands; Oncode Institute, Utrecht, the Netherlands.

作者： Chloé S,Baron ^[1] ; Aditya,Barve ^[1] ; Mauro J,Muraro ^[2] ; Reinier,van der Linden ^[1] ; Gitanjali,Dharmadhikari ^[3] ; Anna,Lyubimova ^[1] ; Eelco J P,de Koning ^[4] ; Alexander,van Oudenaarden ^[5]

作者单位： Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center, Utrecht, the Netherlands; Oncode Institute, Utrecht, the Netherlands. ^[1] Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center, Utrecht, the Netherlands; Oncode Institute, Utrecht, the Netherlands; Single Cell Discoveries, Utrecht, the Netherlands. ^[2] Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center, Utrecht, the Netherlands. ^[3] Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center, Utrecht, the Netherlands; Section of Nephrology and Section of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands. ^[4] Hubrecht Institute-KNAW (Royal Netherlands Academy of Arts and Sciences) and University Medical Center, Utrecht, the Netherlands; Oncode Institute, Utrecht, the Netherlands. Electronic address: a.vanoudenaarden@hubrecht.eu. ^[5]

关键词 FACS gate prediction and normalization bisulphite sequencing cell type purification flow cytometry human pancreas machine learning optimization algorithm single-cell transcriptomics zebrafish hematopoiesis