Understanding TCR affinity, antigen specificity, and cross-reactivity to improve TCR gene-modified T cells for cancer immunotherapy.
第一作者:
Timothy T,Spear
第一单位:
Department of Surgery, Cardinal Bernardin Cancer Center, Loyola University Chicago, 2160 S. 1st Ave, Bldg 112, Room 308, Maywood, IL, 60153, USA. tspear@luc.edu.
作者:
主题词
动物(Animals);抗体特异性(Antibody Specificity);交叉反应(Cross Reactions);细胞毒性, 免疫(Cytotoxicity, Immunologic);基因, T细胞受体(Genes, T-Cell Receptor);人类(Humans);免疫疗法(Immunotherapy);肿瘤(Neoplasms);T细胞抗原受体特异性(T-Cell Antigen Receptor Specificity);T淋巴细胞(T-Lymphocytes)
DOI
10.1007/s00262-019-02401-0
PMID
31595324
发布时间
2024-04-27
- 浏览4
Cancer immunology, immunotherapy
1881-1889页
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