Cellular Processing of the ABCG2 Transporter-Potential Effects on Gout and Drug Metabolism.

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作者： Orsolya,Mózner ^[1] ; Zsuzsa,Bartos ^[2] ; Boglárka,Zámbó ^[3] ; László,Homolya ^[4] ; Tamás,Hegedűs ^[5] ; Balázs,Sarkadi ^[6]

作者单位： Institute of Enzymology, Research Centre for Natural Sciences, Magyar Tudosok krt. 2, 1117 Budapest, Hungary. mozner.orsolya@ttk.hu. ^[1] Institute of Enzymology, Research Centre for Natural Sciences, Magyar Tudosok krt. 2, 1117 Budapest, Hungary. bartos.zsuzsa@ttk.mta.hu.;MTA-SE Molecular Biophysics Research Group, Hungarian Academy of Sciences, Tűzoltó u. 37-47, 1094 Budapest, Hungary. bartos.zsuzsa@ttk.mta.hu. ^[2] Institute of Enzymology, Research Centre for Natural Sciences, Magyar Tudosok krt. 2, 1117 Budapest, Hungary. zambo.boglarka@gmail.com. ^[3] Institute of Enzymology, Research Centre for Natural Sciences, Magyar Tudosok krt. 2, 1117 Budapest, Hungary. homolya.laszlo@ttk.mta.hu. ^[4] MTA-SE Molecular Biophysics Research Group, Hungarian Academy of Sciences, Tűzoltó u. 37-47, 1094 Budapest, Hungary. tamas@hegelab.org.;Department of Biophysics and Radiation Biology, Semmelweis University, Tűzoltó u. 37-47, 1094 Budapest, Hungary. tamas@hegelab.org. ^[5] Institute of Enzymology, Research Centre for Natural Sciences, Magyar Tudosok krt. 2, 1117 Budapest, Hungary. sarkadi@biomembrane.hu.;Department of Biophysics and Radiation Biology, Semmelweis University, Tűzoltó u. 37-47, 1094 Budapest, Hungary. sarkadi@biomembrane.hu. ^[6]

关键词 ABC transporters ABCG2 multidrug transporter ABCG2 trafficking drug metabolism gout

主题词疾病遗传易感性(Genetic Predisposition to Disease);痛风(Gout);人类(Humans);突变(Mutation);肿瘤蛋白质类(Neoplasm Proteins);多态现象, 遗传(Polymorphism, Genetic);蛋白质转运(Protein Transport)

DOI 10.3390/cells8101215

PMID 31597297

发布时间 2024-07-21

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Cells

2019年8卷10期

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Cellular Processing of the ABCG2 Transporter-Potential Effects on Gout and Drug Metabolism.

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Cellular Processing of the ABCG2 Transporter-Potential Effects on Gout and Drug Metabolism.

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