Astilbin prevents bone loss in ovariectomized mice through the inhibition of RANKL-induced osteoclastogenesis.
第一作者:
Haiming,Jin
第一单位:
Key Laboratory of Orthopaedics of Zhejiang Province, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.;School of Biomedical Sciences, The University of Western Australia, Perth, WA, Australia.
作者:
医学主题词
动物(Animals);骨质吸收(Bone Resorption);细胞, 培养的(Cells, Cultured);中草药(Drugs, Chinese Herbal);女(雌)性(Female);黄酮醇类(Flavonols);基因表达(Gene Expression);人类(Humans);整合素β3(Integrin beta3);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);NFATC转录因子类(NFATC Transcription Factors);破骨细胞(Osteoclasts);骨生成(Osteogenesis);卵巢切除术(Ovariectomy);植物药疗法(Phytotherapy);原癌基因蛋白质c-fos(Proto-Oncogene Proteins c-fos);RANK配体(RANK Ligand)
DOI
10.1111/jcmm.14713
PMID
31603626
发布时间
2023-10-19
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