换一批
换一批Disease-associated polymorphisms within the conserved ECR1 enhancer differentially regulate the tissue-specific activity of the cannabinoid-1 receptor gene promoter; implications for cannabinoid pharmacogenetics.
作者：
主题词
大麻酚类(Cannabinoids);细胞, 培养的(Cells, Cultured);计算生物学(Computational Biology);保守序列(Conserved Sequence);疾病易感性(Disease Susceptibility);增强子元件, 遗传学(Enhancer Elements, Genetic);基因表达调控(Gene Expression Regulation);基因, 报告(Genes, Reporter);基因, fos(Genes, fos);人类(Humans);器官特异性(Organ Specificity);遗传药理学(Pharmacogenetics);多态性, 单核苷酸(Polymorphism, Single Nucleotide);启动区, 遗传(Promoter Regions, Genetic);受体, 大麻酚, CB1(Receptor, Cannabinoid, CB1)
DOI
10.1002/humu.23931
PMID
31608546
发布时间
2021-05-19
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Human mutation
291-298页
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