Docosahexaenoic Acid Suppresses Silica-Induced Inflammasome Activation and IL-1 Cytokine Release by Interfering With Priming Signal.

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第一作者： Kathryn A,Wierenga

第一单位： Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, United States.

作者： Kathryn A,Wierenga ^[1] ; Josephine,Wee ^[2] ; Kristen N,Gilley ^[3] ; Lichchavi D,Rajasinghe ^[3] ; Melissa A,Bates ^[3] ; Mikhail A,Gavrilin ^[2] ; Andrij,Holian ^[3] ; James J,Pestka ^[4]

作者单位： Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, United States. ^[1] Institute for Integrative Toxicology, Michigan State University, East Lansing, MI, United States. ^[2] Department of Food Science and Human Nutrition, Michigan State University, East Lansing, MI, United States. ^[3] Division of Pulmonary, Critical Care and Sleep Medicine, Ohio State University, Columbus, OH, United States. ^[4] Department of Biomedical and Pharmaceutical Sciences, Center for Environmental Health Sciences, University of Montana, Missoula, MT, United States. ^[5] Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI, United States. ^[6]

关键词 cell death in vitro inflammasome macrophage omega-3 fatty acids silica