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Multicenter Evaluation of Circulating Cell-Free DNA Extraction and Downstream Analyses for the Development of Standardized (Pre)analytical Work Flows.

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第一作者： Rita,Lampignano

第一单位： Bayer AG, Biomarker Research, Wuppertal, Germany.

作者： Rita,Lampignano ^[1] ; Martin H D,Neumann ^[1] ; Sabrina,Weber ^[2] ; Vera,Kloten ^[1] ; Andrei,Herdean ^[3] ; Thorsten,Voss ^[4] ; Daniel,Groelz ^[4] ; Anna,Babayan ^[5] ; Marco,Tibbesma ^[6] ; Martin,Schlumpberger ^[7] ; Francesca,Chemi ^[8] ; Dominic G,Rothwell ^[8] ; Harriet,Wikman ^[5] ; Jean-Pierre,Galizzi ^[9] ; Inger,Riise Bergheim ^[10] ; Hege,Russnes ^[10] ; Benedetta,Mussolin ^[11] ; Serena,Bonin ^[12] ; Christine,Voigt ^[13] ; Hanny,Musa ^[14] ; Pamela,Pinzani ^[15] ; Evi,Lianidou ^[16] ; Ged,Brady ^[8] ; Michael R,Speicher ^[17] ; Klaus,Pantel ^[5] ; Fay,Betsou ^[18] ; Ed,Schuuring ^[6] ; Mikael,Kubista ^[3] ; Wim,Ammerlaan ^[18] ; Markus,Sprenger-Haussels ^[7] ; Thomas,Schlange ^[1] ; Ellen,Heitzer ^[2]

作者单位： Bayer AG, Biomarker Research, Wuppertal, Germany. ^[1] Institute of Human Genetics, Diagnostic and Research Center for Molecular BioMedicine, Medical University of Graz, Graz, Austria.;Christian Doppler Laboratory for Liquid Biopsies for Early Detection of Cancer, Graz, Austria. ^[2] TATAA Biocenter Ab, Gothenburg, Sweden. ^[3] PreAnalytiX GmbH, Hombrechtikon, Switzerland. ^[4] University Medical Center Hamburg-Eppendorf, Hamburg, Germany. ^[5] University of Groningen, University Medical Center of Groningen, Groningen, the Netherlands. ^[6] QIAGEN GmbH, Hilden, Germany. ^[7] CR-UK Manchester Institute, University of Manchester, Manchester, UK. ^[8] Servier, Suresnes, France. ^[9] Department of Cancer Genetics, Institute of Cancer Research, Oslo University Hospital, Oslo, Norway. ^[10] Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy. ^[11] University of Trieste, DSM-Cattinara Hospital, Trieste, Italy. ^[12] Alacris Theranostics GmbH, Berlin, Germany. ^[13] Boehringer-Ingelheim, Ingelheim am Rhein, Germany. ^[14] University of Florence, Florence, Italy. ^[15] University of Athens, Athens, Greece. ^[16] Institute of Human Genetics, Diagnostic and Research Center for Molecular BioMedicine, Medical University of Graz, Graz, Austria. ^[17] Integrated BioBank of Luxembourg, Dudelange, Luxembourg. ^[18]