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Multidimensional imaging provides evidence for down-regulation of T cell effector function by MDSC in human cancer tissue.

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第一作者： Yu,Si

第一单位： Department of Otorhinolaryngology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany.;Department of Otolaryngology, Head and Neck Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.

作者： Yu,Si ^[1] ; Simon F,Merz ^[2] ; Philipp,Jansen ^[3] ; Baoxiao,Wang ^[1] ; Kirsten,Bruderek ^[4] ; Petra,Altenhoff ^[4] ; Stefan,Mattheis ^[4] ; Stephan,Lang ^[5] ; Matthias,Gunzer ^[6] ; Joachim,Klode ^[3] ; Anthony,Squire ^[6] ; Sven,Brandau ^[7]

作者单位： Department of Otorhinolaryngology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany.;Department of Otolaryngology, Head and Neck Surgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. ^[1] Institute for Experimental Immunology and Imaging, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.;Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. ^[2] Department of Dermatology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. ^[3] Department of Otorhinolaryngology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany. ^[4] Department of Otorhinolaryngology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany.;German Cancer Consortium (DKTK), Partner Site University Hospital Essen, Essen, Germany. ^[5] Institute for Experimental Immunology and Imaging, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. ^[6] Department of Otorhinolaryngology, University of Duisburg-Essen, University Hospital Essen, Essen, Germany. sven.brandau@uk-essen.de.;German Cancer Consortium (DKTK), Partner Site University Hospital Essen, Essen, Germany. ^[7]

医学主题词成年人(Adult);老年人(Aged);癌, 鳞状细胞(Carcinoma, Squamous Cell);减量调节(Down-Regulation);女(雌)性(Female);人类(Humans);喉肿瘤(Laryngeal Neoplasms);男(雄)性(Male);中年人(Middle Aged);口腔肿瘤(Mouth Neoplasms);T淋巴细胞(T-Lymphocytes)

DOI 10.1126/sciimmunol.aaw9159

PMID 31628161

发布时间 2020-07-29

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Multidimensional imaging provides evidence for down-regulation of T cell effector function by MDSC in human cancer tissue.

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Multidimensional imaging provides evidence for down-regulation of T cell effector function by MDSC in human cancer tissue.

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