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The antimicrobial peptide PFR induces necroptosis mediated by ER stress and elevated cytoplasmic calcium and mitochondrial ROS levels: cooperation with Ara-C to act against acute myeloid leukemia.

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第一作者： Yudie,Lv

第一单位： 1College of Life Sciences and Medicine, Zhejiang Sci-Tech University, 310018 Hangzhou, China.;2College of Life Sciences, China Jiliang University, 310018 Hangzhou, China.

作者： Yudie,Lv ^[1] ; Gang,Shao ^[1] ; Qiyu,Zhang ^[2] ; Xi,Wang ^[3] ; Yueming,Meng ^[2] ; Lingfei,Wang ^[3] ; Feiyan,Huang ^[4] ; Tianxin,Yang ^[5] ; Yuanting,Jin ^[6] ; Caiyun,Fu ^[2]

作者单位： 1College of Life Sciences and Medicine, Zhejiang Sci-Tech University, 310018 Hangzhou, China.;2College of Life Sciences, China Jiliang University, 310018 Hangzhou, China. ^[1] 1College of Life Sciences and Medicine, Zhejiang Sci-Tech University, 310018 Hangzhou, China. ^[2] Department of Oncology, The 903rd Hospital of PLA, 310013 Hangzhou, China. ^[3] 4Clinical laboratory, Zhejiang Provincial Hospital of TCM, 310006 Hangzhou, China. ^[4] Department of Hematology, Zhejiang Province People's Hospital, 310014 Hangzhou, China. ^[5] 2College of Life Sciences, China Jiliang University, 310018 Hangzhou, China. ^[6]

关键词 Drug development Haematological cancer

DOI 10.1038/s41392-019-0073-6

PMID 31637016

发布时间 2023-08-17

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The antimicrobial peptide PFR induces necroptosis mediated by ER stress and elevated cytoplasmic calcium and mitochondrial ROS levels: cooperation with Ara-C to act against acute myeloid leukemia.

Signal transduction and targeted therapy

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The antimicrobial peptide PFR induces necroptosis mediated by ER stress and elevated cytoplasmic calcium and mitochondrial ROS levels: cooperation with Ara-C to act against acute myeloid leukemia.

Signal transduction and targeted therapy

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同项目论文

Signal transduction and targeted therapy

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