SIK2 promotes reprogramming of glucose metabolism through PI3K/AKT/HIF-1α pathway and Drp1-mediated mitochondrial fission in ovarian cancer.

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作者： Tian,Gao ^[1] ; Xiaohong,Zhang ^[1] ; Jing,Zhao ^[2] ; Feng,Zhou ^[2] ; Yaya,Wang ^[3] ; Zheng,Zhao ^[4] ; Jinliang,Xing ^[2] ; Biliang,Chen ^[5] ; Jibin,Li ^[6] ; Shujuan,Liu ^[7]

作者单位： Department of Gynaecology and Obstetrics, Xijing Hospital, Fourth Military Medical University, Xi'an, China. ^[1] State Key Laboratory of Cancer Biology and Experimental Teaching Center of Basic Medicine, Fourth Military Medical University, Xi'an, China. ^[2] College of Chemistry and Chemical Engineering, Xi'an University of Science and Technology, Xi'an, China. ^[3] Third Department of Medical Oncology, Shaanxi Provincial Tumor Hospital, Xi'an, China. ^[4] Department of Gynaecology and Obstetrics, Xijing Hospital, Fourth Military Medical University, Xi'an, China. Electronic address: cblxjh@fmmu.edu.cn. ^[5] State Key Laboratory of Cancer Biology and Experimental Teaching Center of Basic Medicine, Fourth Military Medical University, Xi'an, China. Electronic address: ljb871210@fmmu.edu.cn. ^[6] Department of Gynaecology and Obstetrics, Xijing Hospital, Fourth Military Medical University, Xi'an, China. Electronic address: hanliu@fmmu.edu.cn. ^[7]

关键词 Glycolysis Mitochondrial dynamics Oxidative phosphorylation Salt-inducible kinase 2