Sonic hedgehog connects podocyte injury to mesangial activation and glomerulosclerosis.

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作者： Dong,Zhou ^[1] ; Haiyan,Fu ^[2] ; Yang,Han ^[2] ; Lu,Zhang ^[3] ; Shijia,Liu ^[4] ; Lin,Lin ^[1] ; Donna B,Stolz ^[5] ; Youhua,Liu ^[6]

作者单位： Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. ^[1] State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Nanfang Hospital, Southern Medical University, Guangzhou, China. ^[2] Department of Nephrology and. ^[3] Department of Clinical Pharmacology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China. ^[4] Department of Cell Biology and Physiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. ^[5] Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.;State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Nanfang Hospital, Southern Medical University, Guangzhou, China. ^[6]

关键词 Chronic kidney disease Extracellular matrix Nephrology

主题词动物(Animals);细胞系(Cell Line);肾小球肾炎(Glomerulonephritis);猬蛋白质类(Hedgehog Proteins);人类(Humans);男(雄)性(Male);肾小球系膜细胞(Mesangial Cells);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 转基因(Mice, Transgenic);足细胞(Podocytes);蛋白尿(Proteinuria);大鼠, Sprague-Dawley(Rats, Sprague-Dawley)

DOI 10.1172/jci.insight.130515

PMID 31647783

发布时间 2024-09-22

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2019年4卷22期

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Sonic hedgehog connects podocyte injury to mesangial activation and glomerulosclerosis.

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Sonic hedgehog connects podocyte injury to mesangial activation and glomerulosclerosis.

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