Baicalein, an enteric microbial metabolite, suppresses gut inflammation and cancer progression in Apc<sup>Min/+</sup> mice.

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第一作者： C-Z,Wang

第一单位： Tang Center for Herbal Medicine Research, Pritzker School of Medicine, University of Chicago, 5841 S. Maryland Ave., MC 4028, Chicago, IL, 60637, USA. cwang@dacc.uchicago.edu.;Department of Anesthesia and Critical Care, Pritzker School of Medicine, University of Chicago, Chicago, IL, 60637, USA. cwang@dacc.uchicago.edu.

作者： C-Z,Wang ^[1] ; C-F,Zhang ^[2] ; Y,Luo ^[2] ; H,Yao ^[2] ; C,Yu ^[2] ; L,Chen ^[2] ; J,Yuan ^[2] ; W-H,Huang ^[2] ; J-Y,Wan ^[2] ; J,Zeng ^[2] ; W R,Sawadogo ^[2] ; C-S,Yuan ^[3]

作者单位： Tang Center for Herbal Medicine Research, Pritzker School of Medicine, University of Chicago, 5841 S. Maryland Ave., MC 4028, Chicago, IL, 60637, USA. cwang@dacc.uchicago.edu.;Department of Anesthesia and Critical Care, Pritzker School of Medicine, University of Chicago, Chicago, IL, 60637, USA. cwang@dacc.uchicago.edu. ^[1] Tang Center for Herbal Medicine Research, Pritzker School of Medicine, University of Chicago, 5841 S. Maryland Ave., MC 4028, Chicago, IL, 60637, USA.;Department of Anesthesia and Critical Care, Pritzker School of Medicine, University of Chicago, Chicago, IL, 60637, USA. ^[2] Tang Center for Herbal Medicine Research, Pritzker School of Medicine, University of Chicago, 5841 S. Maryland Ave., MC 4028, Chicago, IL, 60637, USA.;Department of Anesthesia and Critical Care, Pritzker School of Medicine, University of Chicago, Chicago, IL, 60637, USA.;Committee on Clinical Pharmacology and Pharmacogenomics, Pritzker School of Medicine, University of Chicago, Chicago, IL, 60637, USA. ^[3]

关键词 Anti-inflammation Antitumor ApcMin/+ mouse model Baicalein (BE)Baicalin (BI)Colorectal cancer Intestinal microbiota Scutellaria baicalensis