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Optogenetic inhibition of Delta reveals digital Notch signalling output during tissue differentiation.

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第一作者： Ranjith,Viswanathan

第一单位： Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.

作者： Ranjith,Viswanathan ^[1] ; Aleksandar,Necakov ^[2] ; Mateusz,Trylinski ^[3] ; Rohit Krishnan,Harish ^[4] ; Daniel,Krueger ^[1] ; Emilia,Esposito ^[1] ; Francois,Schweisguth ^[5] ; Pierre,Neveu ^[6] ; Stefano,De Renzis ^[1]

作者单位： Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany. ^[1] Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.;Department of Biological Science, Brock University, St. Catharines, ON, Canada. ^[2] Institut Pasteur, UMR3738, CNRS, Paris, France.;Sorbonne Université, Paris, France. ^[3] Developmental Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.;Center for Regenerative Therapies Dresden, Technische Universität Dresden, Dresden, Germany. ^[4] Institut Pasteur, UMR3738, CNRS, Paris, France. ^[5] Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany. ^[6]

关键词 Notch signalling morphogenesis optogenetics signal dynamics tissue differentiation