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首页> Schizophrenia research> Association of a functional Claudin-5 variant with schizophrenia in female patients with the 22q11.2 deletion syndrome.

Association of a functional Claudin-5 variant with schizophrenia in female patients with the 22q11.2 deletion syndrome.

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第一作者： Yiran,Guo

第一单位： Center for Data Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, United States.

作者： Yiran,Guo ^[1] ; Larry N,Singh ^[2] ; Yuankun,Zhu ^[1] ; Raquel E,Gur ^[3] ; Adam,Resnick ^[1] ; Stewart A,Anderson ^[3] ; Jorge I,Alvarez ^[4]

作者单位： Center for Data Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, United States. ^[1] Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, United States. ^[2] Department of Psychiatry, The Children's Hospital of Philadelphia (CHOP) and the University of Pennsylvania, United States. ^[3] Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, United States. Electronic address: alvaj@upenn.edu. ^[4]

关键词 22q11.2DS Blood-brain barrier Claudin-5 Neuroinflammation Schizophrenia

主题词成年人(Adult);DiGeorge综合征(DiGeorge Syndrome);女(雌)性(Female);人类(Humans);炎症(Inflammation);男(雄)性(Male);精神分裂症(Schizophrenia);性别因素(Sex Factors)

DOI 10.1016/j.schres.2019.09.014

PMID 31668493

发布时间 2021-01-18

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