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首页> European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences> GMP manufacturing of Vvax001, a therapeutic anti-HPV vaccine based on recombinant viral particles.

GMP manufacturing of Vvax001, a therapeutic anti-HPV vaccine based on recombinant viral particles.

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作者： Annelies,Jorritsma-Smit ^[1] ; Coba J,van Zanten ^[1] ; Jolande,Schoemaker ^[2] ; Janneke J M,Meulenberg ^[2] ; Daan J,Touw ^[1] ; Jos G W,Kosterink ^[3] ; Hans W,Nijman ^[4] ; Toos,Daemen ^[5] ; Derk P,Allersma ^[1]

作者单位： Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, the Netherlands. ^[1] ViciniVax BV, Meditech Center, Groningen, the Netherlands. ^[2] Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, the Netherlands; PharmacoTherapy,- Epidemiology &- Economics, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, the Netherlands. ^[3] Department of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. ^[4] Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. ^[5]

关键词 ATMP GMP Human Papilloma Virus Semliki Forest Virus recombinant viral particles vaccine

主题词动物(Animals);癌症疫苗(Cancer Vaccines);肿瘤(Neoplasms);癌基因蛋白质类, 病毒性(Oncogene Proteins, Viral);乳头状瘤病毒科(Papillomaviridae);乳头瘤病毒E7蛋白质类(Papillomavirus E7 Proteins);乳头状瘤病毒感染(Papillomavirus Infections);质量控制(Quality Control);重组蛋白质类(Recombinant Proteins);阻遏蛋白质类(Repressor Proteins);Vero细胞(Vero Cells);病毒疫苗(Viral Vaccines);病毒粒子(Virion)

DOI 10.1016/j.ejps.2019.105096

PMID 31669389

发布时间 2020-11-17

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European journal of pharmaceutical sciences

105096页

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