Synthesis, characterization, DNA/BSA interactions and in vitro cytotoxicity study of palladium(II) complexes of hispolon derivatives.

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作者： Xiaonan,Wei ^[1] ; Yaxing,Yang ^[1] ; Jiangfeng,Ge ^[1] ; Xue,Lin ^[1] ; Dandan,Liu ^[2] ; Shuxiang,Wang ^[1] ; Jinchao,Zhang ^[1] ; Guoqiang,Zhou ^[3] ; Shenghui,Li ^[4]

作者单位： Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Hebei University, Baoding 071002, China; Key Laboratory of Chemical Biology of Hebei Province, College of Chemistry & Environmental Science, Hebei University, Baoding 071002, China. ^[1] Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Hebei University, Baoding 071002, China; Key Laboratory of Chemical Biology of Hebei Province, College of Chemistry & Environmental Science, Hebei University, Baoding 071002, China. Electronic address: leo-liudan@163.com. ^[2] Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Hebei University, Baoding 071002, China; Key Laboratory of Chemical Biology of Hebei Province, College of Chemistry & Environmental Science, Hebei University, Baoding 071002, China. Electronic address: zhougq1982@163.com. ^[3] Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Hebei University, Baoding 071002, China; Key Laboratory of Chemical Biology of Hebei Province, College of Chemistry & Environmental Science, Hebei University, Baoding 071002, China. Electronic address: lish@hbu.edu.cn. ^[4]

关键词 Antitumor Apoptosis Hispolon Palladium(II) complexes Reactive oxygen species (ROS)