CFTR processing, trafficking and interactions.

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作者： Margarida D,Amaral ^[1] ; Darren M,Hutt ^[2] ; Valeria,Tomati ^[3] ; Hugo M,Botelho ^[1] ; Nicoletta,Pedemonte ^[4]

作者单位： University of Lisboa, Faculty of Sciences, BioISI-Biosystems & Integrative Sciences Institute, Portugal. ^[1] Department of Molecular Medicine, Scripps Research, La Jolla CA, USA. ^[2] UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genova 16147, Italy. ^[3] UOC Genetica Medica, IRCCS Istituto Giannina Gaslini, Via Gerolamo Gaslini 5, Genova 16147, Italy. Electronic address: nicoletta.pedemonte@unige.it. ^[4]

关键词 CFTR Cl-channel CFTR correctors CFTR functional landscape CFTR interactome F508del-CFTR Proteostasis regulators siRNA screening

主题词囊性纤维化(Cystic Fibrosis);囊性纤维化跨膜传导调节因子(Cystic Fibrosis Transmembrane Conductance Regulator);人类(Humans);离子转运(Ion Transport);膜转运调节因子(Membrane Transport Modulators);突变(Mutation)

DOI 10.1016/j.jcf.2019.10.017

PMID 31680043

发布时间 2021-10-12

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准确一般字义偏差语意偏离译文作用小提交