Generation of Organized Porcine Testicular Organoids in Solubilized Hydrogels from Decellularized Extracellular Matrix.

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作者： Maxime,Vermeulen ^[1] ; Federico,Del Vento ^[2] ; Marc,Kanbar ^[3] ; Sébastien,Pyr Dit Ruys ^[4] ; Didier,Vertommen ^[5] ; Jonathan,Poels ^[6] ; Christine,Wyns ^[7]

作者单位： Gynecology-Andrology Research Unit, Institut de Recherche Expérimentale et Clinique, Medical School, Université Catholique de Louvain, 1200 Brussels, Belgium. vermeulen.maxime@live.be. ^[1] Gynecology-Andrology Research Unit, Institut de Recherche Expérimentale et Clinique, Medical School, Université Catholique de Louvain, 1200 Brussels, Belgium. federico.delvento@uclouvain.be. ^[2] Gynecology-Andrology Research Unit, Institut de Recherche Expérimentale et Clinique, Medical School, Université Catholique de Louvain, 1200 Brussels, Belgium. marc.kanbar@uclouvain.be. ^[3] Phosphorylation - MassProt Unit, Institut de Duve, Université Catholique de Louvain, 1200 Brussels, Belgium. sebastien.pyrditruys@uclouvain.be. ^[4] Phosphorylation - MassProt Unit, Institut de Duve, Université Catholique de Louvain, 1200 Brussels, Belgium. didier.vertommen@uclouvain.be. ^[5] Department of Gynecology-Andrology, Cliniques Universitaires Saint-Luc, 1200 Brussels, Belgium. jonathan.poels@uclouvain.be. ^[6] Gynecology-Andrology Research Unit, Institut de Recherche Expérimentale et Clinique, Medical School, Université Catholique de Louvain, 1200 Brussels, Belgium. christine.wyns@uclouvain.be. ^[7] Department of Gynecology-Andrology, Cliniques Universitaires Saint-Luc, 1200 Brussels, Belgium. christine.wyns@uclouvain.be. ^[8]

关键词 artificial testis decellularization extracellular matrix fertility preservation immature testicular tissue organoids spermatogonial stem cells testicular cells three-dimensional culture