Structure of Sonic Hedgehog protein in complex with zinc(II) and magnesium(II) reveals ion-coordination plasticity relevant to peptide drug design.

导出 LinkOut

翻译打印收藏纠错

作者： Rachel,Bonn-Breach ^[1] ; Yu,Gu ^[2] ; Jermaine,Jenkins ^[1] ; Rudi,Fasan ^[2] ; Joseph,Wedekind ^[1]

作者单位： Department of Biochemistry and Biophysics, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, USA. ^[1] Department of Chemistry, University of Rochester, 120 Trustee Road, Rochester, NY 14627, USA. ^[2]

关键词 Mg2+ ions Sonic Hedgehog protein Zn2+ ions cell signaling divalent ion coordination drug design peptide inhibitors protein–protein interactions

主题词结合部位(Binding Sites);药物设计(Drug Design);猬蛋白质类(Hedgehog Proteins);人类(Humans);镁(Magnesium);蛋白质构象(Protein Conformation);锌(Zinc)

DOI 10.1107/S2059798319012890

PMID 31692471

发布时间 2024-07-21

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交

浏览0

Acta crystallographica. Section D, Structural biology

2019年75卷Pt 11期

969-979页

相似文献

中文期刊
外文期刊
学位论文
会议论文

检索历史清除

Structure of Sonic Hedgehog protein in complex with zinc(II) and magnesium(II) reveals ion-coordination plasticity relevant to peptide drug design.

Acta crystallographica. Section D, Structural biology

相似文献

Acta crystallographica. Section D, Structural biology

相关期刊

参考文献：
指定格式：	NoteExpress EndNote RefWorks NoteFirst

检索历史 清除

Structure of Sonic Hedgehog protein in complex with zinc(II) and magnesium(II) reveals ion-coordination plasticity relevant to peptide drug design.

Acta crystallographica. Section D, Structural biology

相似文献

Acta crystallographica. Section D, Structural biology

相关期刊

检索历史清除