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首页> Respiratory research> Aberrant populations of circulating T follicular helper cells and regulatory B cells underlying idiopathic pulmonary fibrosis.

Aberrant populations of circulating T follicular helper cells and regulatory B cells underlying idiopathic pulmonary fibrosis.

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作者： Yuichiro,Asai ^[1] ; Hirofumi,Chiba ^[2] ; Hirotaka,Nishikiori ^[1] ; Ryuta,Kamekura ^[3] ; Hayato,Yabe ^[4] ; Shun,Kondo ^[1] ; Satsuki,Miyajima ^[3] ; Katsunori,Shigehara ^[1] ; Shingo,Ichimiya ^[1] ; Hiroki,Takahashi ^[1]

作者单位： Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, 1-37, South 1-West 16, Chuo-ku, Sapporo, Hokkaido, 060-8543, Japan. ^[1] Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, 1-37, South 1-West 16, Chuo-ku, Sapporo, Hokkaido, 060-8543, Japan. hchiba@sapmed.ac.jp. ^[2] Department of Human Immunology, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan. ^[3] Department of Otolaryngology, Sapporo Medical University School of Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan. ^[4]

关键词 CXCR5 (C-X-C motif chemokine receptor 5)ICOS (inducible co-stimulatory molecule)Idiopathic pulmonary fibrosis (IPF)PD-1 (programmed death 1)T follicular helper cell (Tfh cell)autoimmunity immunity regulatory B cell (Breg cell)

主题词老年人(Aged);老年人, 80以上(Aged, 80 and over);自身免疫(Autoimmunity);CD4淋巴细胞计数(CD4 Lymphocyte Count);病例对照研究(Case-Control Studies);细胞增殖(Cell Proliferation);女(雌)性(Female);人类(Humans);特发性肺纤维化(Idiopathic Pulmonary Fibrosis);免疫, 体液(Immunity, Humoral);肺(Lung);淋巴细胞活化(Lymphocyte Activation);男(雄)性(Male);中年人(Middle Aged);表型(Phenotype);肺弥散能力(Pulmonary Diffusing Capacity);受体, CXCR5(Receptors, CXCR5);T淋巴细胞, 辅助诱导(T-Lymphocytes, Helper-Inducer)

DOI 10.1186/s12931-019-1216-6

PMID 31694639

发布时间 2020-04-27

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Respiratory research

Respiratory research

2019年20卷1期

244页

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