Cytomegalovirus infection is a risk factor for tuberculosis disease in infants.

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作者： Julius,Müller ^[1] ; Rachel,Tanner ^[1] ; Magali,Matsumiya ^[1] ; Margaret A,Snowden ^[2] ; Bernard,Landry ^[2] ; Iman,Satti ^[1] ; Stephanie A,Harris ^[1] ; Matthew K,O'Shea ^[1] ; Lisa,Stockdale ^[1] ; Leanne,Marsay ^[3] ; Agnieszka,Chomka ^[1] ; Rachel,Harrington-Kandt ^[1] ; Zita-Rose Manjaly,Thomas ^[4] ; Vivek,Naranbhai ^[1] ; Elena,Stylianou ^[1] ; Stanley Kimbung,Mbandi ^[5] ; Mark,Hatherill ^[1] ; Gregory,Hussey ^[6] ; Hassan,Mahomed ^[6] ; Michele,Tameris ^[6] ; J Bruce,McClain ^[6] ; Thomas G,Evans ^[6] ; Willem A,Hanekom ^[2] ; Thomas J,Scriba ^[2] ; Helen,McShane ^[6] ; Helen A,Fletcher ^[6]

作者单位： The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom. ^[1] Aeras, Rockville, Maryland, USA. ^[2] London School of Hygiene & Tropical Medicine, London, United Kingdom. ^[3] The Kennedy Institute and. ^[4] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom. ^[5] South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine & Division of Immunology, Department of Pathology, University of Cape Town, South Africa. ^[6]

关键词 Inflammation NK cells Tuberculosis Vaccines

主题词卡介苗(BCG Vaccine);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);病例对照研究(Case-Control Studies);巨细胞病毒(Cytomegalovirus);巨细胞病毒感染(Cytomegalovirus Infections);女(雌)性(Female);人类(Humans);婴儿(Infant);炎症(Inflammation);干扰素γ(Interferon-gamma);杀伤细胞, 天然(Killer Cells, Natural);淋巴细胞活化(Lymphocyte Activation);男(雄)性(Male);结核分枝杆菌(Mycobacterium tuberculosis);危险因素(Risk Factors);南非(South Africa);结核(Tuberculosis)

DOI 10.1172/jci.insight.130090

PMID 31697647

发布时间 2024-02-14

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