Dynamic DNA Energy Landscapes and Substrate Complexity in Triplet Repeat Expansion and DNA Repair.

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第一作者： Jens,Völker

第一单位： Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ 08854, USA.

作者： Jens,Völker ^[1] ; G Eric,Plum ^[2] ; Vera,Gindikin ^[1] ; Kenneth J,Breslauer ^[3]

作者单位： Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ 08854, USA. ^[1] IBET Inc, Columbus, OH 43220, USA. ^[2] Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ 08854, USA.;The Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901, USA. ^[3]

关键词 8oxoG lesion DNA energy landscapes abasic site lesion base excision repair (BER)differential scanning calorimetry (DSC)dynamic DNA states triplet repeat expansion (TRE)

主题词 DNA(DNA);DNA损伤(DNA Damage);DNA修复(DNA Repair);核酸构象(Nucleic Acid Conformation);热力学(Thermodynamics);三核苷酸重复扩增(Trinucleotide Repeat Expansion)

DOI 10.3390/biom9110709

PMID 31698848

发布时间 2020-08-25

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Biomolecules

2019年9卷11期

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Dynamic DNA Energy Landscapes and Substrate Complexity in Triplet Repeat Expansion and DNA Repair.

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Dynamic DNA Energy Landscapes and Substrate Complexity in Triplet Repeat Expansion and DNA Repair.

Biomolecules

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Biomolecules

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